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KMID : 1037020170060010010
Medical Lasers; Engineering, Basic Research, and Clinical Application
2017 Volume.6 No. 1 p.10 ~ p.16
Medical Lasers; Engineering, Basic Research, and Clinical Application
Rho Nark-Kyoung

Abstract
Background and Objectives: To determine the efficacy and safety of a novel 1,927 nm fractional thulium laser system in treating moderate-to-severe melasma in Korean subjects.

Materials and Methods: This study is a retrospective chart and photographic review of 68 Korean women (Fitzpatrick skin type III?IV, mean age of 43.9 yr) with a clinical diagnosis of melasma treated with a novel 1,927 nm fractional thulium laser system. Two independent and blinded investigators evaluated the Melasma Area Severity Index (MASI) scores for each patient, based on clinical photography.

Results: A total of 204 consecutive treatment sessions in 68 patients were included in the analysis. The mean MASI scores decreased from 10.7 ¡¾ 5.3 to 7.6 ¡¾ 4.6, at 2 weeks after 3 consecutive laser treatments (p=0.0001). The subjective assessment of patients revealed that 33 out of 68 subjects were successful in clearing more than 50% of their melasma. Mild and transient postinflammatory hyperpigmentation developed in three patients. Two patients experienced worsening of pre-existing acne. Sixty patients were successfully followed-up (mean 4.1 months), and the recurrence rate was 21.7%.

Conclusion: The novel 1,927 nm fractional thulium laser resurfacing appears to be safe and effective for melasma treatment in the Korean population.
KEYWORD
Asian, Fractional laser, Korean, Melasma, Thulium laser
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